Jaime obtained his Ph.D. from the Albert Einstein College of Medicine with a focus on the biomedical sciences. At Einstein his researched focused in the field of autophagy, specifically centered around one of the three main forms of autophagy, Chaperone-mediated Autophagy (CMA). His research efforts established the first signaliing mechanism discovered to regulate CMA via the retinoic acid-signaling pathway.
In the Rao Lab, Jaime's efforts will focus on studying the overall role of miRNA in B-lymphocyte activation. Specifically, Jaime plans to (1) identify and characterize microRNA-dependent regulation of B-cell activation and terminal differentiation.; (2) characterize B-lymphomagenesis as a function of tumor suppressor microRNA's; and (3) characterize the molecular mechanisms of miRNA-mediated regulation in B-cell development and B-cell lymphoma.